Immune Cell Function and Interaction

Most cited papers

1. Innate Immune RecognitionAnnual Review of Immunology · 2002 · 8,466 citations
2. Obesity is associated with macrophage accumulation in adipose tissueJournal of Clinical Investigation · 2003 · 8,440 citations
3. Control of Regulatory T Cell Development by the Transcription Factor Foxp3Science · 2003 · 8,242 citations
4. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.The Journal of Immunology · 1986 · 7,559 citations
5. Cancer immunotherapy using checkpoint blockadeScience · 2018 · 7,000 citations
6. Interleukin-10 and the Interleukin-10 ReceptorAnnual Review of Immunology · 2001 · 6,795 citations
7. Immunobiology of Dendritic CellsAnnual Review of Immunology · 2000 · 6,675 citations
8. Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical OutcomeScience · 2006 · 6,670 citations
9. Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and PromotionScience · 2011 · 6,614 citations
10. Macrophage plasticity and polarization: in vivo veritasJournal of Clinical Investigation · 2012 · 6,514 citations
11. Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling ProteinsScience · 1994 · 6,160 citations
12. What's wrong with Bonferroni adjustmentsBMJ · 1998 · 5,955 citations
13. Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumorsScience · 2017 · 5,745 citations
14. HLH‐2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosisPediatric Blood & Cancer · 2006 · 5,464 citations
15. PD-1 and Its Ligands in Tolerance and ImmunityAnnual Review of Immunology · 2008 · 5,443 citations
16. Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte ActivationThe Journal of Experimental Medicine · 2000 · 5,360 citations
17. The M1 and M2 paradigm of macrophage activation: time for reassessmentF1000Prime Reports · 2014 · 4,822 citations
18. Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3The Journal of Experimental Medicine · 2003 · 4,726 citations
19. Obesity induces a phenotypic switch in adipose tissue macrophage polarizationJournal of Clinical Investigation · 2007 · 4,688 citations
20. Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal TumorsScience · 1998 · 4,518 citations
21. Biologic basis for interleukin-1 in diseaseBlood · 1996 · 4,383 citations
22. CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding ProteinScience · 1990 · 4,040 citations
23. Enhancement of Antitumor Immunity by CTLA-4 BlockadeScience · 1996 · 4,018 citations
24. Multiple significance tests: the Bonferroni methodBMJ · 1995 · 3,977 citations
25. Of Mice and Not Men: Differences between Mouse and Human ImmunologyThe Journal of Immunology · 2004 · 3,897 citations
26. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.The Journal of Experimental Medicine · 1991 · 3,831 citations
27. TLR4 links innate immunity and fatty acid–induced insulin resistanceJournal of Clinical Investigation · 2006 · 3,705 citations
28. PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's LymphomaNew England Journal of Medicine · 2014 · 3,599 citations
29. Phenotypic Analysis of Antigen-Specific T LymphocytesScience · 1996 · 3,588 citations
30. A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human MelanomaScience · 1991 · 3,580 citations
31. The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicityProceedings of the National Academy of Sciences · 2009 · 3,563 citations
32. Differentiation of Effector CD4 T Cell PopulationsAnnual Review of Immunology · 2010 · 3,521 citations
33. Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic TransplantsScience · 2002 · 3,414 citations
34. M-1/M-2 Macrophages and the Th1/Th2 ParadigmThe Journal of Immunology · 2000 · 3,358 citations
35. Immunogenic Cell Death in Cancer TherapyAnnual Review of Immunology · 2012 · 3,342 citations
36. N aturally A rising CD4+R egulatory T C ells for I mmunologic S elf -T olerance and N egative C ontrol of I mmune R esponsesAnnual Review of Immunology · 2003 · 3,317 citations
37. Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling PathwayScience · 2003 · 3,276 citations
38. Development of T H 1 CD4 + T Cells Through IL-12 Produced by Listeria -Induced MacrophagesScience · 1993 · 3,162 citations
39. The Immunological Synapse: A Molecular Machine Controlling T Cell ActivationScience · 1999 · 3,145 citations
40. Tolerogenic Dendritic CellsAnnual Review of Immunology · 2003 · 3,142 citations
41. Central Memory and Effector Memory T Cell Subsets: Function, Generation, and MaintenanceAnnual Review of Immunology · 2004 · 3,121 citations
42. Activation of NK Cells and T Cells by NKG2D, a Receptor for Stress-Inducible MICAScience · 1999 · 3,021 citations
43. CTLA-4 Control over Foxp3 + Regulatory T Cell FunctionScience · 2008 · 2,965 citations
44. CELLULAR RESPONSES TO INTERFERON-γAnnual Review of Immunology · 1997 · 2,922 citations
45. Regulatory T Cells: Mechanisms of Differentiation and FunctionAnnual Review of Immunology · 2007 · 2,916 citations
46. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular cloneJournal of Virology · 1986 · 2,914 citations
47. Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 + T CellsScience · 1995 · 2,902 citations
48. Lymphocyte Homing and HomeostasisScience · 1996 · 2,879 citations
49. Innate or Adaptive Immunity? The Example of Natural Killer CellsScience · 2011 · 2,842 citations
50. Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4Science · 1995 · 2,781 citations