Yasushi Onishi
Tohoku University
1 paper in the Anchorcite directory, published in 2008, cited 2,965 times in total.
ORCID profileResearch topics
- Immune Cell Function and Interaction · 1 paper
- T-cell and B-cell Immunology · 1 paper
- Cancer Immunotherapy and Biomarkers · 1 paper
Frequent co-authors
- Kajsa Wing · 1 paper
- Paz Prieto-Martin · 1 paper
- Tomoyuki Yamaguchi · 1 paper
- Makoto Miyara · 1 paper
- Zoltán Fehérvári · 1 paper
- Takashi Nomura · 1 paper
- Shimon Sakaguchi · 1 paper
Papers
- CTLA-4 Control over Foxp3 + Regulatory T Cell FunctionScience · 2008 · 2,965 citations
Naturally occurring Foxp3+CD4+ regulatory T cells (Tregs) are essential for maintaining immunological self-tolerance and immune homeostasis. Here, we show that a specific deficiency of cytotoxic T lymphocyte antigen 4 (CTLA-4) in Tregs results in spontaneous development of systemic lymphoproliferation, fatal…
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