Cancer Immunotherapy and Biomarkers

Most cited papers

1. Cancer immunotherapy using checkpoint blockadeScience · 2018 · 7,000 citations
2. Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical OutcomeScience · 2006 · 6,670 citations
3. Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and PromotionScience · 2011 · 6,614 citations
4. Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumorsScience · 2017 · 5,745 citations
5. PD-1 and Its Ligands in Tolerance and ImmunityAnnual Review of Immunology · 2008 · 5,443 citations
6. Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte ActivationThe Journal of Experimental Medicine · 2000 · 5,360 citations
7. Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patientsScience · 2017 · 4,879 citations
8. Enhancement of Antitumor Immunity by CTLA-4 BlockadeScience · 1996 · 4,018 citations
9. Multiple significance tests: the Bonferroni methodBMJ · 1995 · 3,977 citations
10. PD-1 Blockade with Nivolumab in Relapsed or Refractory Hodgkin's LymphomaNew England Journal of Medicine · 2014 · 3,599 citations
11. CTLA-4 Control over Foxp3 + Regulatory T Cell FunctionScience · 2008 · 2,965 citations