Takashi Nomura

Research topics

• Immune Cell Function and Interaction · 2 papers
• T-cell and B-cell Immunology · 2 papers
• CAR-T cell therapy research · 1 paper
• Cancer Immunotherapy and Biomarkers · 1 paper

Frequent co-authors

• Shimon Sakaguchi · 2 papers
• Shohei Hori · 1 paper
• Kajsa Wing · 1 paper
• Yasushi Onishi · 1 paper
• Paz Prieto-Martin · 1 paper
• Tomoyuki Yamaguchi · 1 paper
• Makoto Miyara · 1 paper
• Zoltán Fehérvári · 1 paper

Papers

1. Control of Regulatory T Cell Development by the Transcription Factor Foxp3Science · 2003 · 8,242 citations

   Regulatory T cells engage in the maintenance of immunological self-tolerance by actively suppressing self-reactive lymphocytes. Little is known, however, about the molecular mechanism of their development. Here we show that Foxp3, which encodes a transcription factor that is genetically defective…

2. CTLA-4 Control over Foxp3 + Regulatory T Cell FunctionScience · 2008 · 2,965 citations

   Naturally occurring Foxp3+CD4+ regulatory T cells (Tregs) are essential for maintaining immunological self-tolerance and immune homeostasis. Here, we show that a specific deficiency of cytotoxic T lymphocyte antigen 4 (CTLA-4) in Tregs results in spontaneous development of systemic lymphoproliferation, fatal…