Jan J. Enghild
Duke University
1 paper in the Anchorcite directory, published in 1993, cited 4,321 times in total.
ORCID profileResearch topics
Frequent co-authors
- Warren J. Strittmatter · 1 paper
- Ann M. Saunders · 1 paper
- D. E. Schmechel · 1 paper
- Margaret A. Pericak‐Vance · 1 paper
- Guy S. Salvesen · 1 paper
- Allen D. Roses · 1 paper
Papers
- Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.Proceedings of the National Academy of Sciences · 1993 · 4,321 citations
Apolipoprotein E is immunochemically localized to the senile plaques, vascular amyloid, and neurofibrillary tangles of Alzheimer disease. In vitro, apolipoprotein E in cerebrospinal fluid binds to synthetic beta A4 peptide (the primary constituent of the senile plaque) with high avidity.…
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