Cholinesterase and Neurodegenerative Diseases

Most cited papers

1. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to TherapeuticsScience · 2002 · 14,041 citations
2. Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset FamiliesScience · 1993 · 9,614 citations
3. Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA NeurotoxicityNeurosignals · 2012 · 9,013 citations
4. Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseAlzheimer s & Dementia · 2011 · 7,314 citations
5. Alzheimer's Disease: Genes, Proteins, and TherapyPhysiological Reviews · 2001 · 6,114 citations
6. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.Proceedings of the National Academy of Sciences · 1993 · 4,321 citations
7. A new rating scale for Alzheimer's diseaseAmerican Journal of Psychiatry · 1984 · 4,235 citations
8. β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACEScience · 1999 · 3,910 citations
9. Alzheimer's Disease and Senile Dementia: Loss of Neurons in the Basal ForebrainScience · 1982 · 3,642 citations
10. Diffusible, nonfibrillar ligands derived from Aβ 1–42 are potent central nervous system neurotoxinsProceedings of the National Academy of Sciences · 1998 · 3,550 citations