Allen D. Roses

Research topics

• Alzheimer's disease research and treatments · 2 papers
• Cholinesterase and Neurodegenerative Diseases · 1 paper
• Nuclear Receptors and Signaling · 1 paper
• Dementia and Cognitive Impairment Research · 1 paper
• Amyloidosis: Diagnosis, Treatment, Outcomes · 1 paper

Frequent co-authors

• Ann M. Saunders · 2 papers
• Warren J. Strittmatter · 2 papers
• D. E. Schmechel · 2 papers
• Jeffery M. Vance · 2 papers
• Elizabeth H. Corder · 1 paper
• Perry C. Gaskell · 1 paper
• Gary W. Small · 1 paper
• J. L. Haines · 1 paper

Papers

1. Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset FamiliesScience · 1993 · 9,614 citations

   The apolipoprotein E type 4 allele (APOE-epsilon 4) is genetically associated with the common late onset familial and sporadic forms of Alzheimer's disease (AD). Risk for AD increased from 20% to 90% and mean age at onset decreased from 84…

2. Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's diseaseNeurology · 1993 · 3,829 citations

   Apolipoprotein E, type epsilon 4 allele (APOE epsilon 4), is associated with late-onset familial Alzheimer's disease (AD). There is high avidity and specific binding of amyloid beta-peptide with the protein ApoE. To test the hypothesis that late-onset familial AD may…