Robert L. Coffman

Research topics

• Immune Cell Function and Interaction · 2 papers
• T-cell and B-cell Immunology · 2 papers
• Monoclonal and Polyclonal Antibodies Research · 1 paper
• Immunotherapy and Immune Responses · 1 paper

Frequent co-authors

• Timothy R. Mosmann · 1 paper
• Holly M. Cherwinski · 1 paper
• M W Bond · 1 paper
• Martin A Giedlin · 1 paper
• Kevin W. Moore · 1 paper
• René de Waal Malefyt · 1 paper
• Anne O’Garra · 1 paper

Papers

1. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.The Journal of Immunology · 1986 · 7,559 citations

   A panel of antigen-specific mouse helper T cell clones was characterized according to patterns of lymphokine activity production, and two types of T cell were distinguished. Type 1 T helper cells (TH1) produced IL 2, interferon-gamma, GM-CSF, and IL 3…

2. Interleukin-10 and the Interleukin-10 ReceptorAnnual Review of Immunology · 2001 · 6,795 citations

   Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on most hemopoietic cell types. The principal routine function of IL-10 appears to be…