Monoclonal and Polyclonal Antibodies Research

Most cited papers

1. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proceedings of the National Academy of Sciences · 1979 · 53,826 citations
2. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.Journal of Histochemistry & Cytochemistry · 1981 · 14,260 citations
3. Comprehensive molecular portraits of human breast tumoursNature · 2012 · 12,671 citations
4. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.The Journal of Immunology · 1986 · 7,559 citations
5. Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian CancerScience · 1989 · 6,873 citations
6. Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus InfectionNew England Journal of Medicine · 2002 · 6,413 citations
7. Glide: A New Approach for Rapid, Accurate Docking and Scoring. 2. Enrichment Factors in Database ScreeningJournal of Medicinal Chemistry · 2004 · 5,354 citations
8. Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast CancerNew England Journal of Medicine · 2005 · 5,137 citations
9. The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic TargetsDigestive Diseases · 2014 · 4,858 citations
10. Models for the Specific Adhesion of Cells to CellsScience · 1978 · 4,449 citations
11. Trastuzumab-Induced Hepatotoxicity: A Case ReportBreast Care · 2013 · 4,416 citations
12. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.The Journal of Immunology · 1984 · 4,240 citations
13. HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorScience · 1996 · 4,236 citations
14. Filamentous Fusion Phage: Novel Expression Vectors That Display Cloned Antigens on the Virion SurfaceScience · 1985 · 4,183 citations
15. Optimal computer folding of large RNA sequences using thermodynamics and auxiliary informationNucleic Acids Research · 1981 · 3,645 citations
16. An Assay for Circulating Antibodies to a Major Etiologic Virus of Human Non-A, Non-B HepatitisScience · 1989 · 3,378 citations
17. RGD AND OTHER RECOGNITION SEQUENCES FOR INTEGRINSAnnual Review of Cell and Developmental Biology · 1996 · 3,209 citations
18. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).Journal of Histochemistry & Cytochemistry · 1984 · 3,208 citations
19. Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of FunctionalityAngewandte Chemie International Edition · 2009 · 3,195 citations
20. Improved protein–ligand docking using GOLDProteins Structure Function and Bioinformatics · 2003 · 3,115 citations
21. VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccinesBMC Bioinformatics · 2007 · 3,107 citations
22. Peptide therapeutics: current status and future directionsDrug Discovery Today · 2014 · 3,091 citations
23. A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living SystemsJournal of the American Chemical Society · 2004 · 3,062 citations
24. Integrins and Signal Transduction Pathways: the Road TakenScience · 1995 · 2,983 citations
25. ComplementNew England Journal of Medicine · 2001 · 2,958 citations
26. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferationInternational Journal of Cancer · 1983 · 2,848 citations
27. Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell LineScience · 1999 · 2,827 citations
28. Drug Discovery: A Historical PerspectiveScience · 2000 · 2,782 citations
29. Printing Proteins as Microarrays for High-Throughput Function DeterminationScience · 2000 · 2,772 citations
30. Solvent-Accessible Surfaces of Proteins and Nucleic AcidsScience · 1983 · 2,770 citations
31. Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.The Journal of Experimental Medicine · 1989 · 2,757 citations
32. IgG Subclasses and Allotypes: From Structure to Effector FunctionsFrontiers in Immunology · 2014 · 2,757 citations
33. THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTESThe Journal of Experimental Medicine · 1962 · 2,754 citations
34. Receptor Binding and Membrane Fusion in Virus Entry: The Influenza HemagglutininAnnual Review of Biochemistry · 2000 · 2,737 citations
35. Unmutated Ig VH Genes Are Associated With a More Aggressive Form of Chronic Lymphocytic LeukemiaBlood · 1999 · 2,726 citations
36. Light-Directed, Spatially Addressable Parallel Chemical SynthesisScience · 1991 · 2,704 citations
37. Observations on the Systemic Administration of Autologous Lymphokine-Activated Killer Cells and Recombinant Interleukin-2 to Patients with Metastatic CancerNew England Journal of Medicine · 1985 · 2,673 citations