Reisa Anne Sperling

Research topics

• Alzheimer's disease research and treatments · 3 papers
• Dementia and Cognitive Impairment Research · 3 papers
• Health, Environment, Cognitive Aging · 1 paper
• Cholinesterase and Neurodegenerative Diseases · 1 paper
• Intracerebral and Subarachnoid Hemorrhage Research · 1 paper

Frequent co-authors

• Clifford R. Jack · 2 papers
• David Alan Bennett · 2 papers
• María C. Carrillo · 2 papers
• David M. Holtzman · 2 papers
• Thomas J. Montine · 2 papers
• Creighton H. Phelps · 2 papers
• Christopher Cleon Rowe · 2 papers
• Eric Siemers · 2 papers

Papers

1. NIA‐AA Research Framework: Toward a biological definition of Alzheimer's diseaseAlzheimer s & Dementia · 2018 · 10,970 citations

   In 2011, the National Institute on Aging and Alzheimer's Association created separate diagnostic recommendations for the preclinical, mild cognitive impairment, and dementia stages of Alzheimer's disease. Scientific progress in the interim led to an initiative by the National Institute on…

2. Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseAlzheimer s & Dementia · 2011 · 7,314 citations

   The pathophysiological process of Alzheimer's disease (AD) is thought to begin many years before the diagnosis of AD dementia. This long "preclinical" phase of AD would provide a critical opportunity for therapeutic intervention; however, we need to further elucidate the…

3. Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's DiseaseNew England Journal of Medicine · 2012 · 3,918 citations

   BACKGROUND: The order and magnitude of pathologic processes in Alzheimer's disease are not well understood, partly because the disease develops over many years. Autosomal dominant Alzheimer's disease has a predictable age at onset and provides an opportunity to determine the…