David M. Holtzman

Research topics

• Alzheimer's disease research and treatments · 3 papers
• Dementia and Cognitive Impairment Research · 3 papers
• Health, Environment, Cognitive Aging · 1 paper
• Neurological Disease Mechanisms and Treatments · 1 paper
• Intracerebral and Subarachnoid Hemorrhage Research · 1 paper

Frequent co-authors

• María C. Carrillo · 2 papers
• William J. Jagust · 2 papers
• Creighton H. Phelps · 2 papers
• Reisa Anne Sperling · 2 papers
• Nick C. Fox · 2 papers
• Clifford R. Jack · 1 paper
• David Alan Bennett · 1 paper
• Kaj Blennow · 1 paper

Papers

1. NIA‐AA Research Framework: Toward a biological definition of Alzheimer's diseaseAlzheimer s & Dementia · 2018 · 10,970 citations

   In 2011, the National Institute on Aging and Alzheimer's Association created separate diagnostic recommendations for the preclinical, mild cognitive impairment, and dementia stages of Alzheimer's disease. Scientific progress in the interim led to an initiative by the National Institute on…

2. The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseAlzheimer s & Dementia · 2011 · 10,470 citations

   The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of developing criteria for the symptomatic predementia phase of Alzheimer's disease (AD), referred to in this article as mild cognitive impairment due to AD. The…

3. Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's DiseaseNew England Journal of Medicine · 2012 · 3,918 citations

   BACKGROUND: The order and magnitude of pathologic processes in Alzheimer's disease are not well understood, partly because the disease develops over many years. Autosomal dominant Alzheimer's disease has a predictable age at onset and provides an opportunity to determine the…