Philip M. Murphy

Research topics

• Immune Cell Function and Interaction · 2 papers
• T-cell and B-cell Immunology · 2 papers
• HIV Research and Treatment · 2 papers

Frequent co-authors

• Edward A. Berger · 2 papers
• Ghalib Alkhatib · 1 paper
• Christophe Combadière · 1 paper
• Christopher C. Broder · 1 paper
• Yu Feng · 1 paper
• Paul E. Kennedy · 1 paper
• Joshua Marion Farber · 1 paper

Papers

1. CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1Science · 1996 · 2,747 citations

   Human immunodeficiency virus-type 1 (HIV-1) entry requires fusion cofactors on the CD4+ target cell. Fusin, a heterotrimeric GTP-binding protein (G protein)-coupled receptor, serves as a cofactor for T cell line-tropic isolates. The chemokines RANTES, MIP-1alpha, and MIP-1beta, which suppress infection…

2. CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and DiseaseAnnual Review of Immunology · 1999 · 2,203 citations

   In addition to CD4, the human immunodeficiency virus (HIV) requires a coreceptor for entry into target cells. The chemokine receptors CXCR4 and CCR5, members of the G protein-coupled receptor superfamily, have been identified as the principal coreceptors for T cell…