HIV Research and Treatment

Most cited papers

1. AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibilityJournal of Computational Chemistry · 2009 · 26,013 citations
2. Prevention of HIV-1 Infection with Early Antiretroviral TherapyNew England Journal of Medicine · 2011 · 7,006 citations
3. 1993 Revised Classification System for HIV Infection and Expanded Surveillance Case Definition for AIDS Among Adolescents and AdultsClinical Infectious Diseases · 1993 · 4,362 citations
4. HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorScience · 1996 · 4,236 citations
5. Reduction of Maternal-Infant Transmission of Human Immunodeficiency Virus Type 1 with Zidovudine TreatmentNew England Journal of Medicine · 1994 · 3,747 citations
6. HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation TimeScience · 1996 · 3,598 citations
7. A Third-Generation Lentivirus Vector with a Conditional Packaging SystemJournal of Virology · 1998 · 3,424 citations
8. Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and WomenNew England Journal of Medicine · 2012 · 3,338 citations
9. Identification of a Reservoir for HIV-1 in Patients on Highly Active Antiretroviral TherapyScience · 1997 · 3,172 citations
10. Viral Load and Heterosexual Transmission of Human Immunodeficiency Virus Type 1New England Journal of Medicine · 2000 · 3,085 citations
11. Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in ThailandNew England Journal of Medicine · 2009 · 3,078 citations
12. The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related ComplexNew England Journal of Medicine · 1987 · 3,003 citations
13. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular cloneJournal of Virology · 1986 · 2,914 citations
14. Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 + T CellsScience · 1995 · 2,902 citations
15. Initiation of Antiretroviral Therapy in Early Asymptomatic HIV InfectionNew England Journal of Medicine · 2015 · 2,851 citations
16. Full-Length Human Immunodeficiency Virus Type 1 Genomes from Subtype C-Infected Seroconverters in India, with Evidence of Intersubtype RecombinationJournal of Virology · 1999 · 2,777 citations
17. CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1Science · 1996 · 2,747 citations
18. Prognosis in HIV-1 Infection Predicted by the Quantity of Virus in PlasmaScience · 1996 · 2,720 citations
19. A Controlled Trial of Two Nucleoside Analogues plus Indinavir in Persons with Human Immunodeficiency Virus Infection and CD4 Cell Counts of 200 per Cubic Millimeter or LessNew England Journal of Medicine · 1997 · 2,688 citations
20. Updated research nosology for HIV-associated neurocognitive disordersNeurology · 2007 · 2,634 citations
21. Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural GeneScience · 1996 · 2,518 citations
22. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndromeJournal of Virology · 1994 · 2,516 citations
23. Not So Different After All: A Comparison of Methods for Detecting Amino Acid Sites Under SelectionMolecular Biology and Evolution · 2005 · 2,513 citations
24. Antiretroviral Treatment of Adult HIV InfectionJAMA · 2012 · 2,475 citations
25. A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell NucleusJournal of Biological Chemistry · 1997 · 2,390 citations
26. HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapyNeurology · 2010 · 2,385 citations
27. Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma ViremiaScience · 1997 · 2,256 citations
28. CD4+ Count–Guided Interruption of Antiretroviral TreatmentNew England Journal of Medicine · 2006 · 2,250 citations
29. Control of Viremia in Simian Immunodeficiency Virus Infection by CD8 + LymphocytesScience · 1999 · 2,206 citations
30. CHEMOKINE RECEPTORS AS HIV-1 CORECEPTORS: Roles in Viral Entry, Tropism, and DiseaseAnnual Review of Immunology · 1999 · 2,203 citations
31. Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α TherapyScience · 1998 · 2,131 citations
32. Plasma Viral Load and CD4+ Lymphocytes as Prognostic Markers of HIV-1 InfectionAnnals of Internal Medicine · 1997 · 2,096 citations
33. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapyProceedings of the National Academy of Sciences · 1997 · 2,034 citations
34. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brainCell · 1986 · 2,018 citations
35. HIV Population Dynamics in Vivo: Implications for Genetic Variation, Pathogenesis, and TherapyScience · 1995 · 2,005 citations
36. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infectionProceedings of the National Academy of Sciences · 2008 · 1,977 citations
37. The Spectrum of Engagement in HIV Care and its Relevance to Test-and-Treat Strategies for Prevention of HIV InfectionClinical Infectious Diseases · 2011 · 1,936 citations
38. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trialThe Lancet · 2015 · 1,925 citations
39. Treatment with Indinavir, Zidovudine, and Lamivudine in Adults with Human Immunodeficiency Virus Infection and Prior Antiretroviral TherapyNew England Journal of Medicine · 1997 · 1,925 citations
40. Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an InhibitorScience · 1992 · 1,923 citations