Patrice D. Cani

Research topics

• Gut microbiota and health · 5 papers
• Probiotics and Fermented Foods · 3 papers
• Adipokines, Inflammation, and Metabolic Diseases · 2 papers
• Diet and metabolism studies · 1 paper
• Microbial Metabolites in Food Biotechnology · 1 paper
• Barrier Structure and Function Studies · 1 paper

Frequent co-authors

• Nathalie M. Delzenne · 3 papers
• Claude Knauf · 2 papers
• Audrey M. Neyrinck · 2 papers
• Aurélie Waget · 2 papers
• Glenn R. Gibson · 2 papers
• Rémy Burcelin · 2 papers
• Amandine Everard · 2 papers
• Jacques Amar · 1 paper

Papers

1. Metabolic Endotoxemia Initiates Obesity and Insulin ResistanceDiabetes · 2007 · 6,698 citations

   Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a low-grade inflammation. Seeking an inflammatory factor causative of the onset of insulin resistance, obesity, and diabetes, we have identified bacterial lipopolysaccharide (LPS) as a triggering factor. We…

2. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebioticsNature Reviews Gastroenterology & Hepatology · 2017 · 5,620 citations

   With the continued interest in the role of the gut microbiota in health, attention has now turned to how to harness the microbiota for the benefit of the host. This Consensus Statement outlines the definition and scope of the term…

3. Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in MiceDiabetes · 2008 · 4,851 citations

   OBJECTIVE: Diabetes and obesity are characterized by a low-grade inflammation whose molecular origin is unknown. We previously determined, first, that metabolic endotoxemia controls the inflammatory tone, body weight gain, and diabetes, and second, that high-fat feeding modulates gut microbiota and…

4. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesityProceedings of the National Academy of Sciences · 2013 · 4,574 citations

   Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial composition and the mechanisms of interaction with the host that affect gut barrier function during obesity and type 2 diabetes have not been…

5. Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecologyGut · 2015 · 1,938 citations

   OBJECTIVE: Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut microbial species and microbial gene richness. Abundance of Akkermansia muciniphila, a mucin-degrading bacterium, has been inversely associated with body fat…