Nathalie M. Delzenne

Research topics

• Gut microbiota and health · 3 papers
• Adipokines, Inflammation, and Metabolic Diseases · 2 papers
• Diet and metabolism studies · 1 paper
• Barrier Structure and Function Studies · 1 paper
• Tryptophan and brain disorders · 1 paper
• Probiotics and Fermented Foods · 1 paper

Frequent co-authors

• Patrice D. Cani · 3 papers
• Claude Knauf · 2 papers
• Audrey M. Neyrinck · 2 papers
• Aurélie Waget · 2 papers
• Rémy Burcelin · 2 papers
• Jacques Amar · 1 paper
• Miguel A. Iglesias · 1 paper
• Marjorie Poggi · 1 paper

Papers

1. Metabolic Endotoxemia Initiates Obesity and Insulin ResistanceDiabetes · 2007 · 6,698 citations

   Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a low-grade inflammation. Seeking an inflammatory factor causative of the onset of insulin resistance, obesity, and diabetes, we have identified bacterial lipopolysaccharide (LPS) as a triggering factor. We…

2. Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in MiceDiabetes · 2008 · 4,851 citations

   OBJECTIVE: Diabetes and obesity are characterized by a low-grade inflammation whose molecular origin is unknown. We previously determined, first, that metabolic endotoxemia controls the inflammatory tone, body weight gain, and diabetes, and second, that high-fat feeding modulates gut microbiota and…

3. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesityProceedings of the National Academy of Sciences · 2013 · 4,574 citations

   Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial composition and the mechanisms of interaction with the host that affect gut barrier function during obesity and type 2 diabetes have not been…