Laurence Zitvogel

Research topics

• Immune Cell Function and Interaction · 3 papers
• Cancer Immunotherapy and Biomarkers · 2 papers
• Gut microbiota and health · 2 papers
• Dermatology and Skin Diseases · 1 paper
• Immunotherapy and Immune Responses · 1 paper
• Adenosine and Purinergic Signaling · 1 paper

Frequent co-authors

• Emmanuelle Le Chatelier · 2 papers
• Nicolas Pons · 2 papers
• Guido Kroemer · 2 papers
• Bertrand Routy · 1 paper
• Lisa Derosa · 1 paper
• Connie P.M. Duong · 1 paper
• Maryam Tidjani Alou · 1 paper
• Romain Daillère · 1 paper

Papers

1. Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumorsScience · 2017 · 5,745 citations

   Good bacteria help fight cancer Resident gut bacteria can affect patient responses to cancer immunotherapy (see the Perspective by Jobin). Routy et al. show that antibiotic consumption is associated with poor response to immunotherapeutic PD-1 blockade. They profiled samples from…

2. Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patientsScience · 2017 · 4,879 citations

   Good bacteria help fight cancer Resident gut bacteria can affect patient responses to cancer immunotherapy (see the Perspective by Jobin). Routy et al. show that antibiotic consumption is associated with poor response to immunotherapeutic PD-1 blockade. They profiled samples from…

3. Immunogenic Cell Death in Cancer TherapyAnnual Review of Immunology · 2012 · 3,342 citations

   Depending on the initiating stimulus, cancer cell death can be immunogenic or nonimmunogenic. Immunogenic cell death (ICD) involves changes in the composition of the cell surface as well as the release of soluble mediators, occurring in a defined temporal sequence.…

4. Innate or Adaptive Immunity? The Example of Natural Killer CellsScience · 2011 · 2,842 citations

   Natural killer (NK) cells were originally defined as effector lymphocytes of innate immunity endowed with constitutive cytolytic functions. More recently, a more nuanced view of NK cells has emerged. NK cells are now recognized to express a repertoire of activating…