Cole Trapnell
University of Maryland, College Park
2 papers in the Anchorcite directory, published in 2009, cited 35,666 times in total.
ORCID profileResearch topics
- RNA and protein synthesis mechanisms · 2 papers
- Genomics and Phylogenetic Studies · 1 paper
- Algorithms and Data Compression · 1 paper
- RNA Research and Splicing · 1 paper
- RNA regulation and disease · 1 paper
Frequent co-authors
- Steven L. Salzberg · 2 papers
- Ben Langmead · 1 paper
- Mihai Pop · 1 paper
- Lior S. Pachter · 1 paper
Papers
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeGenome biology · 2009 · 23,395 citations
Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of approximately…
- TopHat: discovering splice junctions with RNA-SeqBioinformatics · 2009 · 12,271 citations
MOTIVATION: A new protocol for sequencing the messenger RNA in a cell, known as RNA-Seq, generates millions of short sequence fragments in a single run. These fragments, or 'reads', can be used to measure levels of gene expression and to…
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