Steven L. Salzberg
Johns Hopkins University
4 papers in the Anchorcite directory, published between 2001 and 2014, cited 54,386 times in total.
ORCID profileResearch topics
- Genomics and Phylogenetic Studies · 3 papers
- RNA and protein synthesis mechanisms · 3 papers
- Algorithms and Data Compression · 1 paper
- Genomics and Chromatin Dynamics · 1 paper
- RNA Research and Splicing · 1 paper
- RNA regulation and disease · 1 paper
Frequent co-authors
- Cole Trapnell · 2 papers
- Ben Langmead · 1 paper
- Mihai Pop · 1 paper
- J. Craig Venter · 1 paper
- Mark D. Adams · 1 paper
- Eugene Wimberly Myers · 1 paper
- Peter W. Li · 1 paper
- Richard Mural · 1 paper
Papers
- Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeGenome biology · 2009 · 23,395 citations
Bowtie is an ultrafast, memory-efficient alignment program for aligning short DNA sequence reads to large genomes. For the human genome, Burrows-Wheeler indexing allows Bowtie to align more than 25 million reads per CPU hour with a memory footprint of approximately…
- The Sequence of the Human GenomeScience · 2001 · 13,708 citations
A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage…
- TopHat: discovering splice junctions with RNA-SeqBioinformatics · 2009 · 12,271 citations
MOTIVATION: A new protocol for sequencing the messenger RNA in a cell, known as RNA-Seq, generates millions of short sequence fragments in a single run. These fragments, or 'reads', can be used to measure levels of gene expression and to…
- Kraken: ultrafast metagenomic sequence classification using exact alignmentsGenome biology · 2014 · 5,012 citations
Kraken is an ultrafast and highly accurate program for assigning taxonomic labels to metagenomic DNA sequences. Previous programs designed for this task have been relatively slow and computationally expensive, forcing researchers to use faster abundance estimation programs, which only classify…
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