RNA and protein synthesis mechanisms

Most cited papers

1. Gapped BLAST and PSI-BLAST: a new generation of protein database search programsNucleic Acids Research · 1997 · 75,091 citations
2. DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences · 1977 · 69,531 citations
3. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceNucleic Acids Research · 1994 · 65,374 citations
4. STAR: ultrafast universal RNA-seq alignerBioinformatics · 2012 · 58,430 citations
5. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.Proceedings of the National Academy of Sciences · 1979 · 53,826 citations
6. MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and UsabilityMolecular Biology and Evolution · 2013 · 50,278 citations
7. MUSCLE: multiple sequence alignment with high accuracy and high throughputNucleic Acids Research · 2004 · 47,425 citations
8. Cutadapt removes adapter sequences from high-throughput sequencing readsEMBnet journal · 2011 · 37,307 citations
9. RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genomeBMC Bioinformatics · 2011 · 24,108 citations
10. Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeGenome biology · 2009 · 23,395 citations
11. HTSeq—a Python framework to work with high-throughput sequencing dataBioinformatics · 2014 · 23,354 citations
12. An integrated encyclopedia of DNA elements in the human genomeNature · 2012 · 19,912 citations
13. MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transformNucleic Acids Research · 2002 · 18,272 citations
14. Minimap2: pairwise alignment for nucleotide sequencesBioinformatics · 2018 · 17,805 citations
15. Scalable molecular dynamics with NAMDJournal of Computational Chemistry · 2005 · 17,570 citations
16. FastTree 2 – Approximately Maximum-Likelihood Trees for Large AlignmentsPLoS ONE · 2010 · 16,480 citations
17. MolProbity : all-atom structure validation for macromolecular crystallographyActa Crystallographica Section D Biological Crystallography · 2009 · 14,920 citations
18. Prodigal: prokaryotic gene recognition and translation initiation site identificationBMC Bioinformatics · 2010 · 13,803 citations
19. Mfold web server for nucleic acid folding and hybridization predictionNucleic Acids Research · 2003 · 13,718 citations
20. The Sequence of the Human GenomeScience · 2001 · 13,708 citations
21. Fast and accurate long-read alignment with Burrows–Wheeler transformBioinformatics · 2010 · 13,175 citations
22. A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEffFly · 2012 · 13,038 citations
23. AFLP: a new technique for DNA fingerprintingNucleic Acids Research · 1995 · 12,465 citations
24. Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequencesBioinformatics · 2006 · 12,464 citations
25. TopHat: discovering splice junctions with RNA-SeqBioinformatics · 2009 · 12,271 citations
26. MEME SUITE: tools for motif discovery and searchingNucleic Acids Research · 2009 · 11,751 citations
27. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiNucleic Acids Research · 1983 · 11,638 citations
28. Improved tools for biological sequence comparison.Proceedings of the National Academy of Sciences · 1988 · 11,371 citations
29. tRNAscan-SE: A Program for Improved Detection of Transfer RNA Genes in Genomic SequenceNucleic Acids Research · 1997 · 11,340 citations
30. Database resources of the National Center for Biotechnology Information: updateNucleic Acids Research · 2003 · 10,979 citations
31. Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA PolymeraseScience · 1990 · 10,524 citations
32. A PHOTOMETRIC ADAPTATION OF THE SOMOGYI METHOD FOR THE DETERMINATION OF GLUCOSEJournal of Biological Chemistry · 1944 · 10,417 citations
33. InterProScan 5: genome-scale protein function classificationBioinformatics · 2014 · 10,406 citations
34. Tandem repeats finder: a program to analyze DNA sequencesNucleic Acids Research · 1999 · 10,155 citations
35. RNA-Guided Human Genome Engineering via Cas9Science · 2013 · 9,569 citations
36. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.Genetics · 1989 · 8,844 citations
37. UniProt: a worldwide hub of protein knowledgeNucleic Acids Research · 2018 · 8,547 citations
38. dbSNP: the NCBI database of genetic variationNucleic Acids Research · 2001 · 7,965 citations
39. Optimal computer folding of large RNA sequences using thermodynamics and auxiliary informationNucleic Acids Research · 1981 · 3,645 citations
40. Not So Different After All: A Comparison of Methods for Detecting Amino Acid Sites Under SelectionMolecular Biology and Evolution · 2005 · 2,513 citations