PHENIX : building new software for automated crystallographic structure determination
Paul D. Adams, Ralf W. Grosse‐Kunstleve, Li‐Wei Hung, Thomas R. Ioerger, Airlie J. McCoy, Nigel W. Moriarty, Randy J. Read, James C. Sacchettini, Nicholas K. Sauter, Thomas C. Terwilliger
Acta Crystallographica Section D Biological Crystallography · 2002 · 4,427 citationsOpen access
Abstract
Structural genomics seeks to expand rapidly the number of protein structures in order to extract the maximum amount of information from genomic sequence databases. The advent of several large-scale projects worldwide leads to many new challenges in the field of crystallographic macromolecular structure determination. A novel software package called PHENIX (Python-based Hierarchical ENvironment for Integrated Xtallography) is therefore being developed. This new software will provide the necessary algorithms to proceed from reduced intensity data to a refined molecular model and to facilitate structure solution for both the novice and expert crystallographer.
Cite this paper
Adams, P. D., Grosse‐Kunstleve, R. W., Hung, L., Ioerger, T. R., McCoy, A. J., Moriarty, N. W., Read, R. J., Sacchettini, J. C., Sauter, N. K., & Terwilliger, T. C. (2002). PHENIX : building new software for automated crystallographic structure determination. Acta Crystallographica Section D Biological Crystallography, 58(11), 1948–1954. https://doi.org/10.1107/s0907444902016657
Read it with every claim anchored
Add this paper to a project, ask questions of it, and get answers that point to the exact passage.
Start freeRelated papers
- A short history of SHELX2007
- UCSF Chimera—A visualization system for exploratory research and analysis2004
- Highly accurate protein structure prediction with AlphaFold2021
- AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading2009
- Features and development of Coot2010
Metadata from OpenAlex (CC0). Citations are generated from the published record.