Randy J. Read

Research topics

• Protein Structure and Dynamics · 5 papers
• Enzyme Structure and Function · 5 papers
• Microbial Metabolic Engineering and Bioproduction · 1 paper
• Crystallization and Solubility Studies · 1 paper
• Advanced NMR Techniques and Applications · 1 paper
• Computational Drug Discovery Methods · 1 paper

Frequent co-authors

• Paul D. Adams · 4 papers
• Ralf W. Grosse‐Kunstleve · 4 papers
• Airlie J. McCoy · 4 papers
• Li‐Wei Hung · 2 papers
• Nigel W. Moriarty · 2 papers
• Thomas C. Terwilliger · 2 papers
• Martyn Winn · 2 papers
• Pavel V. Afonine · 1 paper

Papers

1. PHENIX : a comprehensive Python-based system for macromolecular structure solutionActa Crystallographica Section D Biological Crystallography · 2010 · 24,964 citations

   Macromolecular X-ray crystallography is routinely applied to understand biological processes at a molecular level. However, significant time and effort are still required to solve and complete many of these structures because of the need for manual interpretation of complex numerical…

2. Phaser crystallographic softwareJournal of Applied Crystallography · 2007 · 21,424 citations

   Phaser is a program for phasing macromolecular crystal structures by both molecular replacement and experimental phasing methods. The novel phasing algorithms implemented in Phaser have been developed using maximum likelihood and multivariate statistics. For molecular replacement, the new algorithms have…

3. Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationActa Crystallographica Section D Biological Crystallography · 1998 · 15,802 citations

   A new software suite, called Crystallography & NMR System (CNS), has been developed for macromolecular structure determination by X-ray crystallography or solution nuclear magnetic resonance (NMR) spectroscopy. In contrast to existing structure-determination programs, the architecture of CNS is highly flexible,…

4. Overview of the CCP 4 suite and current developmentsActa Crystallographica Section D Biological Crystallography · 2011 · 12,716 citations

   The CCP4 (Collaborative Computational Project, Number 4) software suite is a collection of programs and associated data and software libraries which can be used for macromolecular structure determination by X-ray crystallography. The suite is designed to be flexible, allowing users…

5. PHENIX : building new software for automated crystallographic structure determinationActa Crystallographica Section D Biological Crystallography · 2002 · 4,427 citations

   Structural genomics seeks to expand rapidly the number of protein structures in order to extract the maximum amount of information from genomic sequence databases. The advent of several large-scale projects worldwide leads to many new challenges in the field of…