William E. Klunk

Research topics

• Alzheimer's disease research and treatments · 3 papers
• Dementia and Cognitive Impairment Research · 3 papers
• Frailty in Older Adults · 1 paper
• Neurological Disease Mechanisms and Treatments · 1 paper
• Intracerebral and Subarachnoid Hemorrhage Research · 1 paper

Frequent co-authors

• Richard P Mayeux · 2 papers
• John C. Morris · 2 papers
• Martin N. Rossor · 2 papers
• Guy M. McKhann · 1 paper
• David S. Knopman · 1 paper
• Howard Mark Chertkow · 1 paper
• Bradley T. Hyman · 1 paper
• Clifford R. Jack · 1 paper

Papers

1. The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's diseaseAlzheimer s & Dementia · 2011 · 19,187 citations

   The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of revising the 1984 criteria for Alzheimer's disease (AD) dementia. The workgroup sought to ensure that the revised criteria would be flexible enough to be…

2. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐BAnnals of Neurology · 2004 · 4,546 citations

   This report describes the first human study of a novel amyloid-imaging positron emission tomography (PET) tracer, termed Pittsburgh Compound-B (PIB), in 16 patients with diagnosed mild AD and 9 controls. Compared with controls, AD patients typically showed marked retention of…

3. Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's DiseaseNew England Journal of Medicine · 2012 · 3,918 citations

   BACKGROUND: The order and magnitude of pathologic processes in Alzheimer's disease are not well understood, partly because the disease develops over many years. Autosomal dominant Alzheimer's disease has a predictable age at onset and provides an opportunity to determine the…