R. C. Edgar
1 paper in the Anchorcite directory, published in 2004, cited 47,425 times in total.
ORCID profileResearch topics
- Genomics and Phylogenetic Studies · 1 paper
- RNA and protein synthesis mechanisms · 1 paper
- Glycosylation and Glycoproteins Research · 1 paper
Papers
- MUSCLE: multiple sequence alignment with high accuracy and high throughputNucleic Acids Research · 2004 · 47,425 citations
We describe MUSCLE, a new computer program for creating multiple alignments of protein sequences. Elements of the algorithm include fast distance estimation using kmer counting, progressive alignment using a new profile function we call the log-expectation score, and refinement using…
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