James E. Darnell Jr.
Rockefeller University
1 paper in the Anchorcite directory, published in 1994, cited 6,160 times in total.
Research topics
- Immune Cell Function and Interaction · 1 paper
- Cytokine Signaling Pathways and Interactions · 1 paper
- Pharmacological Effects of Natural Compounds · 1 paper
Frequent co-authors
- lan M. Kerr · 1 paper
- George Robert Stark · 1 paper
Papers
- Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling ProteinsScience · 1994 · 6,160 citations
Through the study of transcriptional activation in response to interferon alpha (IFN-alpha) and interferon gamma (IFN-gamma), a previously unrecognized direct signal transduction pathway to the nucleus has been uncovered: IFN-receptor interaction at the cell surface leads to the activation of…
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