Heng Li
Broad Institute
2 papers in the Anchorcite directory, published between 2010 and 2018, cited 30,980 times in total.
ORCID profileResearch topics
- Genomics and Phylogenetic Studies · 2 papers
- RNA and protein synthesis mechanisms · 2 papers
- Protein Structure and Dynamics · 1 paper
- Algorithms and Data Compression · 1 paper
Frequent co-authors
- Richard M. Durbin · 1 paper
Papers
- Minimap2: pairwise alignment for nucleotide sequencesBioinformatics · 2018 · 17,805 citations
Motivation: Recent advances in sequencing technologies promise ultra-long reads of ∼100 kb in average, full-length mRNA or cDNA reads in high throughput and genomic contigs over 100 Mb in length. Existing alignment programs are unable or inefficient to process such…
- Fast and accurate long-read alignment with Burrows–Wheeler transformBioinformatics · 2010 · 13,175 citations
Abstract Motivation: Many programs for aligning short sequencing reads to a reference genome have been developed in the last 2 years. Most of them are very efficient for short reads but inefficient or not applicable for reads >200 bp because…
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