George McDonald Church
Harvard University
1 paper in the Anchorcite directory, published in 2013, cited 9,569 times in total.
ORCID profileResearch topics
- RNA and protein synthesis mechanisms · 1 paper
- Bacterial Genetics and Biotechnology · 1 paper
- CRISPR and Genetic Engineering · 1 paper
Frequent co-authors
- Prashant Mali · 1 paper
- Luhan Yang · 1 paper
- Kevin M. Esvelt · 1 paper
- John Aach · 1 paper
- Marc Güell · 1 paper
- Julie E. Norville · 1 paper
Papers
- RNA-Guided Human Genome Engineering via Cas9Science · 2013 · 9,569 citations
Bacteria and archaea have evolved adaptive immune defenses, termed clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems, that use short RNA to direct degradation of foreign nucleic acids. Here, we engineer the type II bacterial CRISPR system to function…
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