Carolyn Ruth Bertozzi

Research topics

• Monoclonal and Polyclonal Antibodies Research · 2 papers
• Click Chemistry and Applications · 2 papers
• Chemical Synthesis and Analysis · 1 paper
• Protein Degradation and Inhibitors · 1 paper

Frequent co-authors

• Ellen M. Sletten · 1 paper
• Nicholas J. Agard · 1 paper
• Jennifer A. Prescher · 1 paper

Papers

1. Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of FunctionalityAngewandte Chemie International Edition · 2009 · 3,195 citations

   The study of biomolecules in their native environments is a challenging task because of the vast complexity of cellular systems. Technologies developed in the last few years for the selective modification of biological species in living systems have yielded new…

2. A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living SystemsJournal of the American Chemical Society · 2004 · 3,062 citations

   Selective chemical reactions that are orthogonal to the diverse functionality of biological systems have become important tools in the field of chemical biology. Two notable examples are the Staudinger ligation of azides and phosphines and the Cu(I)-catalyzed [3 + 2]…