Arlene H. Sharpe
Brigham and Women's Hospital
1 paper in the Anchorcite directory, published in 2008, cited 5,443 times in total.
ORCID profileResearch topics
- Immune Cell Function and Interaction · 1 paper
- Cancer Immunotherapy and Biomarkers · 1 paper
- Immunotherapy and Immune Responses · 1 paper
Frequent co-authors
- Mary E Keir · 1 paper
- Manish J. Butte · 1 paper
- Gordon James Freeman · 1 paper
Papers
- PD-1 and Its Ligands in Tolerance and ImmunityAnnual Review of Immunology · 2008 · 5,443 citations
Programmed death 1 (PD-1) and its ligands, PD-L1 and PD-L2, deliver inhibitory signals that regulate the balance between T cell activation, tolerance, and immunopathology. Immune responses to foreign and self-antigens require specific and balanced responses to clear pathogens and tumors…
Metadata from OpenAlex (CC0).