Andrew C. Wakeham
University of Toronto
1 paper in the Anchorcite directory, published in 1995, cited 2,781 times in total.
Research topics
- Immune Cell Function and Interaction · 1 paper
- T-cell and B-cell Immunology · 1 paper
- Signaling Pathways in Disease · 1 paper
Frequent co-authors
- Paul D. Waterhouse · 1 paper
- Josef Martin Penninger · 1 paper
- Emma M. Timms · 1 paper
- Arda Shahinian · 1 paper
- Kelvin P. Lee · 1 paper
- Craig B. Thompson · 1 paper
- Henrik Griesser · 1 paper
- Tak W. Mak · 1 paper
Papers
- Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4Science · 1995 · 2,781 citations
The role of the cell-surface molecule CTLA-4 in the regulation of T cell activation has been controversial. Here, lymph nodes and spleens of CTLA-4-deficient mice accumulated T cell blasts with up-regulated activation markers. These blast cells also infiltrated liver, heart,…
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