Prion Diseases and Protein Misfolding

Most cited papers

1. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to TherapeuticsScience · 2002 · 14,041 citations
2. Protein Misfolding, Functional Amyloid, and Human DiseaseAnnual Review of Biochemistry · 2006 · 6,508 citations
3. Amyloid plaque core protein in Alzheimer disease and Down syndrome.Proceedings of the National Academy of Sciences · 1985 · 4,481 citations
4. Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of PathogenesisScience · 2003 · 4,104 citations
5. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology.Proceedings of the National Academy of Sciences · 1986 · 3,717 citations
6. Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque FormationJournal of Neuroscience · 2006 · 3,680 citations