Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology
Nicholas A. Peppas, J. Zach Hilt, Ali Khademhosseini, Róbert Langer
Advanced Materials · 2006 · 4,112 citations
Abstract
Abstract Hydrophilic polymers are the center of research emphasis in nanotechnology because of their perceived “intelligence”. They can be used as thin films, scaffolds, or nanoparticles in a wide range of biomedical and biological applications. Here we highlight recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for these applications. Natural, biohybrid, and synthetic hydrophilic polymers and hydrogels are analyzed and their thermodynamic responses are discussed. In addition, examples of the use of hydrogels for various therapeutic applications are given. We show how such systems' intelligent behavior can be used in sensors, microarrays, and imaging. Finally, we outline challenges for the future in integrating hydrogels into biomedical applications.
Cite this paper
Peppas, N. A., Hilt, J. Z., Khademhosseini, A., & Langer, R. (2006). Hydrogels in biology and medicine: From molecular principles to bionanotechnology. Advanced Materials, 18(11), 1345–1360. https://doi.org/10.1002/adma.200501612
Read it with every claim anchored
Add this paper to a project, ask questions of it, and get answers that point to the exact passage.
Start freeRelated papers
- Piezoelectric Nanogenerators Based on Zinc Oxide Nanowire Arrays2006
- Hydrogel: Preparation, characterization, and applications: A review2013
- Materials and Mechanics for Stretchable Electronics2010
- Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications2019
- Epidermal Electronics2011
Metadata from OpenAlex (CC0). Citations are generated from the published record.