Jeffrey S. Flier
Beth Israel Deaconess Medical Center
1 paper in the Anchorcite directory, published in 2006, cited 3,705 times in total.
ORCID profileResearch topics
- Immune Response and Inflammation · 1 paper
- Immune Cell Function and Interaction · 1 paper
- Adipokines, Inflammation, and Metabolic Diseases · 1 paper
Frequent co-authors
- Hang Shi · 1 paper
- Maia V. Kokoeva · 1 paper
- Karen Inouye · 1 paper
- Iphigenia Tzameli · 1 paper
- Huali Yin · 1 paper
Papers
- TLR4 links innate immunity and fatty acid–induced insulin resistanceJournal of Clinical Investigation · 2006 · 3,705 citations
TLR4 is the receptor for LPS and plays a critical role in innate immunity. Stimulation of TLR4 activates proinflammatory pathways and induces cytokine expression in a variety of cell types. Inflammatory pathways are activated in tissues of obese animals and…
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