Irwin Fridovich
Duke Medical Center
1 paper in the Anchorcite directory, published in 1995, cited 3,471 times in total.
Research topics
- Vanadium and Halogenation Chemistry · 1 paper
- Photosynthetic Processes and Mechanisms · 1 paper
- Metal-Catalyzed Oxygenation Mechanisms · 1 paper
Papers
- SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASESAnnual Review of Biochemistry · 1995 · 3,471 citations
O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity,…
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