David A. Relman

Research topics

• Gut microbiota and health · 3 papers
• Probiotics and Fermented Foods · 1 paper
• Helicobacter pylori-related gastroenterology studies · 1 paper
• Diet and metabolism studies · 1 paper
• Metabolomics and Mass Spectrometry Studies · 1 paper
• Microbial Community Ecology and Physiology · 1 paper

Frequent co-authors

• Paul B. Eckburg · 2 papers
• Steven R. Gill · 2 papers
• Elisabeth M. Bik · 1 paper
• Charles Noah Bernstein · 1 paper
• Elizabeth Purdom · 1 paper
• Les Dethlefsen · 1 paper
• Michael J. Sargent · 1 paper
• Mihai Pop · 1 paper

Papers

1. Diversity of the Human Intestinal Microbial FloraScience · 2005 · 7,995 citations

   The human endogenous intestinal microflora is an essential "organ" in providing nourishment, regulating epithelial development, and instructing innate immunity; yet, surprisingly, basic features remain poorly described. We examined 13,355 prokaryotic ribosomal RNA gene sequences from multiple colonic mucosal sites and…

2. Metagenomic Analysis of the Human Distal Gut MicrobiomeScience · 2006 · 4,726 citations

   The human intestinal microbiota is composed of 10(13) to 10(14) microorganisms whose collective genome ("microbiome") contains at least 100 times as many genes as our own genome. We analyzed approximately 78 million base pairs of unique DNA sequence and 2062…

3. Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics dataMicrobiome · 2018 · 3,716 citations

   BACKGROUND: The accuracy of microbial community surveys based on marker-gene and metagenomic sequencing (MGS) suffers from the presence of contaminants-DNA sequences not truly present in the sample. Contaminants come from various sources, including reagents. Appropriate laboratory practices can reduce contamination,…